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More serious but rarer side effects include pancreatitis, gallbladder disease, worsening of existing diabetic retinopathy, acute kidney injury, and a theoretical risk of certain thyroid tumors based on rodent data

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This combination therapy was approved by the US FDA in 2012 for long-term treatment of obesity in adults with a BMI of 30 kg/sq m or a BMI of more than 27 kg/sq m with at least one weight-related disorder

Modulation of redox homeostasis: a strategy to overcome cancer drug resistance